Pharmaceutical Granulation is a process in which granular substances (medicines), with carrier substances (more inert powders ) are combined. Binding of these drugs in the powder product in the form of tablets. No other tablet can be purely drug then several tests to help mix the perfect Just find a small change in the type and amount of additives that take place there, can have a significant impact on how the drug is effective, with the possibility of tablet, which always deliver exactly the same thing.
Although much research in support can be very expensive and time consuming to test each pill, it is important that the right is found. Once the ideal tool is found, it will help to bind the active ingredient and spread in the body. Can also be flavored tablet more comfortable for the consumer. The coatings can also be used to improve the taste of the tablet, which often contain sugar to sweeten create. The coating can also be issued for the control of drugs in the digestive system, which ensures effective drug release.
The method of pharmaceutical pellets is not the same for all the tablets. Various problems depending on the density or particle size in tablet form, together with other compatibility issues. Herein, the drug can not be mixed with the carrier and separation occur. The tablets can cause problems when consumed or are simply not effective if it is done. It is therefore necessary to ensure fully to ensure that the particles completely bound and with the ability to spread widely. Sometimes, the separation can be obtained by granulation of the active ingredient alone first, and then granulated, thereafter, the liaison, in addition to the formation of the tablet to dissolve.
Why granulation pharmaceutical use ?
The most common form of medication is used worldwide, tablets, making the process of pharmaceutical granulation very commonly used and very important. Tablets for the treatment of many diseases and conditions. They are very comfortable to wear and can be eaten, can not be taken from a liquid dissolves easily without the need for additional hardware. It is a great advantage over other drugs that require at least a measuring cup or syringe.
The person must take a series of pills every day, they are able to take the tablets from their original packaging and put them in boxes for part of each day so that they are better managed and organized. Help pharmaceutical granulation, strong between hard not disintegrate into a fine powder and then can be managed and changed easily.
The ability to avoid the pill crumbles also ensures that there is no loss of active ingredient. This is very important because it not only gets the consumer the same amount each time, but also the right amount during their treatment guaranteed. In addition, hard, strong plates can without crumbling to people who may prefer to swallow small pieces at a time to steal the tablets break into two halves afford.
Machines used for pharmaceutical granulation
Commercial machines for pharmaceutical granulation can be extremely expensive, especially in the testing phase. As extrusion and spheronization equipment necessary to complete the process, can be stored bulky and heavy. Fortunately, there are options for new or smaller pharmaceutical companies that conduct testing to reduce costs and the need for storage space. Some manufacturers offer the option to configure the device so that pharmaceutical companies pay a smaller share and return the product after use.
Alternatively, you can buy smaller versions of machines that are easier to store and cheaper to maintain. A leading provider of small equipment is speronization CALEVA 380 is their spherical body specially designed for small test and production. They also provide car rental for those who only need the machine for short periods or for those who are not willing to invest in large-scale production.